Micro-crystalline collage-containing pharmaceutical compositions useful for topical applications

  • Inventors:
  • Assignees: Avicon Inc
  • Publication Date: March 12, 1975
  • Publication Number: GB-1386864-A


1386864 Ophthalmic compositions AVICON Inc 11 Feb 1972 6586/72 Heading A5B Aqueous pharmaceutical compositions for topical application to the eye having enhanced drug action and/or prolonged duration of drug action comprise a pharmacologically active ophthalmic agent and 0.1 to 5.0% by weight of microcrystalline collagen, based on the composition. The ophthalmic agent may be chloramphenicol, carbomycin, polymyxin, erythromycin, dihydrostreptomycin, neomycin, aureomycin, terramycin, bacitracin, penicillin, ampicillin, atropine, homatropine, scopolamine, cyclopentalate, tropicamide, oxyphenonium, tetracaine, proparacaine, benoxinate, cocaine, procaine, lidocaine, epinephrine, isoniazid, nitrofurans, sulphonamides such as sulphanilamide, sulphapyridine, sulphadiazine, sulphathiazole, sulphaceamide, phenylephrine, ephedrine, gentian violet, acriflarine, silver nitrate, acetylcholine, carbachol, pilocarpine, eserine, echothiophate, demercarium, dihydroergocornine, tolazoline, zinc sulphate, chloro butanol, phenyl butazone, tetraethylammonium chloride, hexamethonium, norepinephrine, physostigmine, cortisone, hydrocortisone, prednisolone, dexamethasone, triamicinolone, methyl prednisilone, argyrol, phenylmercuric nitrate, chlorazene, mercurichrome, iodine or a quaternary ammonium germicide or mixtures thereof.




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Cited By (5)

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    US-5036056-AJuly 30, 1991Martin KludasMethods for treating damaged corneal, uterine, or cartilage tissue
    US-5055298-AOctober 08, 1991Chemisches Laboratorium Dr. Kurt Richter GmbhCosmetic composition comprising an extracellular connective tissue matrix
    US-5679713-AOctober 21, 1997Astra AktiebolagPharmaceutical composition containing carbachol and other cholinergic substances
    WO-2016092513-A1June 16, 2016Alfa Intes Industria Terapeutica Splendore S.R.L.Ophthalmic compositions for use in the treatment of the dry eye syndrome
    WO-8900043-A1January 12, 1989Martin KludasAgent ophtalmique ainsi que ses compositions, et procede de traitement de la cornee